Epimer

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Epimer

Epimer (/ɛpɪmər/) is a term used in Biochemistry to describe one of two stereoisomers that differ in configuration at only one stereogenic center.

Etymology

The term "Epimer" is derived from the Greek word "epimeres" which means "partly". This is in reference to the fact that epimers are partly identical to each other in terms of their molecular structure.

Definition

An Epimer is a type of isomer where two molecules differ in the configuration at only one carbon atom. This carbon atom is known as the epimeric or chiral center. Epimers are a subtype of diastereomers.

Examples

Common examples of epimers include D-glucose and D-mannose, which are epimers of each other at the C-2 position, and D-glucose and D-galactose, which are epimers at the C-4 position.

Related Terms

  • Stereoisomer: A type of isomer where the atoms are connected in the same order but differ in spatial orientation.
  • Diastereomer: A type of stereoisomer that is not a mirror image of another molecule.
  • Chiral center: A carbon atom attached to four different types of atoms or groups of atoms.
  • Isomer: Molecules with the same molecular formula but different structural formulas.

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