Endrin
Endrin is a chlorinated hydrocarbon that has been used as an insecticide, rodenticide, and acaricide. It is a colorless, odorless solid, although commercial samples can be off-white and possess a mild chemical odor.
Chemical Properties
Endrin is a stereoisomer of dieldrin, a related pesticide. It is a solid that is not soluble in water, but is soluble in most organic solvents. It is stable to heat and light, but is broken down by ultraviolet light.
Uses
Endrin was used primarily to control rodents, rabbits, and insects in field crops such as cotton and grains. It was also used to control insects on orchard fruits, and as a seed dressing. Its use has been discontinued in the U.S. since 1986 due to its high toxicity and persistence in the environment.
Health Effects
Exposure to endrin can cause a variety of adverse health effects, including headache, dizziness, nausea, vomiting, seizures, and in severe cases, death. It is also considered a potential human carcinogen.
Environmental Impact
Endrin is highly persistent in the environment, with a half-life of up to 12 years. It can bioaccumulate in fish and birds, leading to secondary poisoning of predators. It is also toxic to bees and other beneficial insects.
Regulation
In the U.S., endrin is classified as a Restricted Use Pesticide (RUP) by the Environmental Protection Agency (EPA). It is also listed as a Persistent Organic Pollutant (POP) under the Stockholm Convention.
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Contributors: Prab R. Tumpati, MD