Effusion

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Effusion

Diagram illustrating the process of effusion.

Effusion is a medical condition characterized by the escape of fluid into a body cavity. This can occur in various parts of the body and is often indicative of an underlying disease or condition. Effusions can be classified based on their location, such as pleural effusion, pericardial effusion, and peritoneal effusion.

Types of Effusion

Pleural Effusion

Pleural effusion is the accumulation of fluid in the pleural space, the area between the lungs and the chest wall. This condition can result from various causes, including congestive heart failure, pneumonia, and malignancy. Symptoms may include dyspnea, chest pain, and cough.

Pericardial Effusion

Pericardial effusion involves the accumulation of fluid in the pericardial cavity surrounding the heart. It can be caused by infections, inflammatory diseases, or trauma. Large effusions can lead to cardiac tamponade, a life-threatening condition that requires immediate medical intervention.

Peritoneal Effusion

Peritoneal effusion, also known as ascites, is the accumulation of fluid in the peritoneal cavity. Common causes include liver cirrhosis, heart failure, and cancer. Patients may experience abdominal distension, discomfort, and weight gain.

Pathophysiology

Effusion occurs when there is an imbalance between the production and absorption of fluid in a body cavity. This can be due to increased capillary permeability, decreased oncotic pressure, or impaired lymphatic drainage. The specific pathophysiological mechanisms vary depending on the type of effusion and its underlying cause.

Diagnosis

The diagnosis of effusion typically involves a combination of clinical evaluation, imaging studies, and laboratory tests. Ultrasound and CT scan are commonly used to visualize effusions. Thoracentesis, pericardiocentesis, or paracentesis may be performed to obtain fluid samples for analysis, which can help determine the cause of the effusion.

Treatment

Treatment of effusion depends on the underlying cause and the severity of the condition. Therapeutic options may include:

  • Drainage: Procedures such as thoracentesis, pericardiocentesis, or paracentesis can be performed to remove excess fluid and relieve symptoms.
  • Medication: Diuretics, antibiotics, or anti-inflammatory drugs may be prescribed based on the underlying cause.
  • Surgery: In some cases, surgical intervention may be necessary to address the underlying condition or to prevent recurrence of the effusion.

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Contributors: Prab R. Tumpati, MD