Dysplastic nevus syndrome
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Dysplastic nevus syndrome | |
|---|---|
| |
| Synonyms | Familial atypical multiple mole melanoma syndrome (FAMMM) |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Multiple atypical moles, increased risk of melanoma |
| Complications | Melanoma, skin cancer |
| Onset | Usually in adolescence or early adulthood |
| Duration | Lifelong |
| Types | N/A |
| Causes | Genetic mutations, often in the CDKN2A gene |
| Risks | Family history of melanoma, fair skin, excessive sun exposure |
| Diagnosis | Skin examination, biopsy |
| Differential diagnosis | Common mole, melanoma, seborrheic keratosis |
| Prevention | Regular skin checks, sun protection |
| Treatment | Monitoring, surgical removal of suspicious moles |
| Medication | N/A |
| Prognosis | Variable, depends on early detection and management |
| Frequency | Rare, but more common in families with a history of melanoma |
| Deaths | N/A |
Dysplastic nevus syndrome is a medical condition characterized by the presence of multiple atypical moles (dysplastic nevi) on the skin. These moles have irregular features under the microscope and may be larger than ordinary moles. People with dysplastic nevus syndrome have a higher risk of developing melanoma, a serious type of skin cancer.
Causes
The exact cause of dysplastic nevus syndrome is unknown. However, it is believed to be due to a combination of genetic and environmental factors. A family history of the condition or of melanoma increases the risk.
Symptoms
People with dysplastic nevus syndrome have multiple atypical moles on their skin. These moles may be larger than ordinary moles and have irregular features under the microscope. They may also change in size, shape, or color over time.
Diagnosis
Diagnosis of dysplastic nevus syndrome is based on the clinical appearance of the moles and a history of atypical moles in the patient or their family. A skin biopsy may be performed to examine the mole under the microscope and confirm the diagnosis.
Treatment
There is no cure for dysplastic nevus syndrome. However, regular skin examinations can help detect changes in the moles early and reduce the risk of developing melanoma. In some cases, atypical moles may be removed to prevent them from becoming cancerous.
Prognosis
With regular skin examinations and early detection of changes in the moles, the prognosis for people with dysplastic nevus syndrome is generally good. However, they have a higher risk of developing melanoma and should be monitored closely.
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Contributors: Prab R. Tumpati, MD
