Doravirine
Doravirine (pronounced: dora-vi-rine) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV (Human Immunodeficiency Virus). It is marketed under the brand name Pifeltro and is also available in combination with lamivudine and tenofovir disoproxil fumarate in a product called Delstrigo.
Etymology
The name "Doravirine" is derived from the class of drugs it belongs to, non-nucleoside reverse transcriptase inhibitors (NNRTIs). The prefix "Dora-" is arbitrary and does not have a specific meaning, while "-virine" is a common suffix for NNRTIs, indicating its function in inhibiting the reverse transcriptase enzyme.
Usage
Doravirine is used in combination with other antiretroviral medications to treat HIV-1 infection in adults who have not previously received antiretroviral therapy or who are replacing their current antiretroviral regimen. It works by blocking the action of reverse transcriptase, an enzyme that the virus needs to multiply.
Related Terms
- Antiretroviral therapy: The use of drugs to manage HIV.
- Reverse transcriptase: An enzyme that HIV needs to multiply.
- Non-nucleoside reverse transcriptase inhibitors (NNRTIs): A class of antiretroviral drugs that includes doravirine.
- HIV-1: The most common and pathogenic strain of the virus.
- Lamivudine and Tenofovir disoproxil fumarate: Other antiretroviral drugs often used in combination with doravirine.
See Also
External links
- Medical encyclopedia article on Doravirine
- Wikipedia's article - Doravirine
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