Dihydrostilbenoid
Dihydroresveratrol is a dihydrostilbenoid, a type of stilbenoid that is a hydrogenated derivative of resveratrol. It is a naturally occurring compound found in certain plants and is known for its potential biological activity.
Chemical Structure
Dihydroresveratrol is characterized by its stilbene backbone, which consists of two phenyl rings connected by a two-carbon ethylene bridge. The hydrogenation of resveratrol results in the saturation of the double bond in the ethylene bridge, forming dihydroresveratrol. This modification can influence the compound's chemical properties and biological activity.
Sources
Dihydroresveratrol can be found in various plant sources, particularly in those that also contain resveratrol. It is often present in the roots and stems of certain plants, where it may play a role in the plant's defense mechanisms against pathogens and environmental stress.
Biological Activity
Dihydroresveratrol has been studied for its potential health benefits, which may include antioxidant, anti-inflammatory, and cardioprotective effects. These properties are thought to be similar to those of resveratrol, although the exact mechanisms and efficacy can vary due to the structural differences between the two compounds.
Metabolism
In humans, dihydroresveratrol can be formed as a metabolite of resveratrol. After the ingestion of resveratrol, it undergoes metabolic transformation in the body, leading to the production of dihydroresveratrol among other metabolites. This process involves the action of intestinal microbiota and liver enzymes.
Potential Applications
Research into dihydroresveratrol is ongoing, with interest in its potential applications in medicine and nutrition. Its role as a metabolite of resveratrol suggests it may contribute to the overall effects observed with resveratrol supplementation. However, more studies are needed to fully understand its bioavailability and therapeutic potential.
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Contributors: Prab R. Tumpati, MD