Dicrocoelium hospes
Dicrocoelium hospes is a species of parasitic fluke that primarily infects the liver of various mammals. It is part of the Dicrocoeliidae family and the Platyhelminthes phylum. The life cycle of Dicrocoelium hospes involves two intermediate hosts, typically a snail and an ant, before it reaches its definitive host.
Life Cycle
The life cycle of Dicrocoelium hospes begins when the adult fluke lays eggs in the bile ducts of the definitive host. These eggs are then excreted in the host's feces. A snail, acting as the first intermediate host, consumes the feces and the eggs hatch into larvae within the snail. The larvae then develop into a stage known as cercariae, which are released by the snail in a slime ball.
The slime ball containing the cercariae is then consumed by an ant, the second intermediate host. Within the ant, the cercariae transform into metacercariae, the infective stage for the definitive host. The metacercariae manipulate the behavior of the ant, causing it to climb to the top of a blade of grass during the night or when the temperature is cool. This increases the likelihood of the ant being consumed by the definitive host, thus completing the life cycle of Dicrocoelium hospes.
Pathology
Infection with Dicrocoelium hospes can lead to a condition known as dicrocoeliasis, which is characterized by inflammation and damage to the liver. Symptoms may include abdominal pain, fatigue, and jaundice. In severe cases, dicrocoeliasis can lead to cirrhosis of the liver.
Treatment and Control
Treatment for Dicrocoelium hospes infection typically involves the use of anthelmintic drugs, such as praziquantel. Control measures include proper sanitation to prevent contamination of grazing areas with feces, and the control of snail and ant populations.
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Contributors: Prab R. Tumpati, MD