Diatragacanth
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Diatragacanth is a traditional pharmaceutical preparation that has been used historically in various medicinal applications. It is primarily composed of tragacanth, a natural gum obtained from the dried sap of several species of Middle Eastern legumes of the genus Astragalus, including Astragalus gummifer.
Composition and Properties
Diatragacanth is known for its thickening and emulsifying properties, which make it useful in the formulation of pastes, creams, and other topical applications. The primary component, tragacanth, is a complex polysaccharide that swells in water to form a gel-like substance. This property is utilized in pharmaceutical formulations to stabilize emulsions and suspensions.
Historical Uses
Historically, diatragacanth was used in traditional medicine for its soothing and demulcent properties. It was often included in preparations intended to treat coughs, sore throats, and other minor irritations of the mucous membranes. The gum's ability to form a protective film over mucous membranes was thought to provide relief from irritation and inflammation.
Modern Applications
In modern pharmacy, the use of diatragacanth has declined with the advent of more refined and standardized excipients. However, it is still occasionally used in compounding pharmacy for its natural thickening properties. It is also used in the food industry as a stabilizer and thickener.
Safety and Toxicology
Diatragacanth is generally considered safe for use in pharmaceutical and food applications. However, as with any natural product, there is a potential for allergic reactions in sensitive individuals. It is important to ensure that the gum is free from contaminants and is used in appropriate concentrations.
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Contributors: Prab R. Tumpati, MD