Destroying angel

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Destroying Angel
Destroying Angel 02

Destroying Angel refers to several highly poisonous mushrooms belonging to the genus Amanita. The most notable species include Amanita virosa (found in Europe), Amanita bisporigera (found in North America), and Amanita ocreata (found in the western United States). These mushrooms are known for their pure white appearance, with a smooth cap, white gills, and a white or pale stalk. The term "Destroying Angel" aptly describes the deadly nature of these mushrooms, as ingestion can lead to severe liver and kidney damage, and without prompt treatment, death.

Identification

Destroying Angel mushrooms can be identified by their distinctive features:

  • Cap: The cap is smooth, white, and can vary in shape from flat to slightly convex.
  • Gills: The gills are free from the stem, densely packed, and white.
  • Stem: It is white, with a ring (or annulus) and a bulbous base that may be buried underground.
  • Spore Print: The spore print of the Destroying Angel is white.

It is crucial for foragers to note that these characteristics can be easily confused with edible species, making proper identification essential.

Toxicity

The primary toxins in Destroying Angel mushrooms are amatoxins, which inhibit RNA polymerase II, a critical enzyme in the synthesis of mRNA. This inhibition leads to cellular apoptosis, particularly affecting the liver and kidneys due to their high metabolic rates. Symptoms of poisoning can appear 6 to 24 hours after ingestion and include vomiting, diarrhea, cramps, and later, severe liver and kidney failure. Without immediate treatment, the mortality rate is high.

Treatment

Treatment for Destroying Angel poisoning focuses on supportive care and may include activated charcoal, to prevent toxin absorption, and aggressive hydration to support kidney function. In severe cases, liver transplantation may be the only option to prevent death. Early medical intervention is critical for survival.

Prevention

Prevention of poisoning by Destroying Angel mushrooms is primarily through education and awareness. Mushroom foragers should follow the adage, "When in doubt, throw it out," and only consume mushrooms that have been positively identified by an expert.

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Contributors: Prab R. Tumpati, MD