Deschloroketamine

Deschloroketamine

Deschloroketamine chemical structure

Deschloroketamine (also known as 2'-Oxo-PCM, DXE, or DCK) is a dissociative anesthetic that belongs to the arylcyclohexylamine class. It is structurally related to ketamine, a well-known anesthetic, but lacks the chlorine atom present in ketamine, which is reflected in its name.

Chemical Structure and Properties

Deschloroketamine is chemically known as 2-(methylamino)-2-phenylcyclohexanone. It is a derivative of ketamine, where the chlorine atom on the phenyl ring is removed. This modification results in a compound with similar but distinct pharmacological properties compared to ketamine.

Deschloroketamine 3D molecular structure

The molecular formula of deschloroketamine is C₁₃H₁₇NO, and it has a molar mass of 203.28 g/mol. The compound is typically encountered as a white crystalline powder.

Pharmacology

Deschloroketamine acts primarily as an NMDA receptor antagonist, similar to ketamine. This action is responsible for its dissociative effects, which include alterations in perception, mood, and consciousness. The compound may also interact with other receptor systems, contributing to its complex pharmacological profile.

Effects and Uses

Deschloroketamine is known for its dissociative effects, which can include sensory detachment, hallucinations, and altered perception of time and space. These effects are dose-dependent and can vary significantly between individuals.

In a clinical context, deschloroketamine has been explored for its potential use as an anesthetic, although it is not as widely used as ketamine. Its use in research settings has been limited, and it is more commonly encountered as a recreational drug.

Legal Status

The legal status of deschloroketamine varies by country. In some jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of approved medical use. In others, it may be available for research purposes under specific regulations.

Safety and Risks

As with other dissociative anesthetics, the use of deschloroketamine carries risks, including the potential for psychological dependence, cognitive impairment, and adverse physical effects. Users may experience confusion, agitation, and in some cases, psychosis. Long-term use can lead to bladder and kidney damage, a condition known as ketamine bladder syndrome.

Related Compounds

Deschloroketamine is part of a broader class of arylcyclohexylamines, which includes:

• Ketamine
• Methoxetamine
• Phencyclidine (PCP)

Related Pages

• Ketamine
• NMDA receptor antagonist
• Dissociative drug