DT-PACE
DT-PACE is a chemotherapy regimen used in the treatment of multiple myeloma. It is an acronym for the drugs used in the regimen: Dexamethasone, Thalidomide, Cisplatin (or Platinol), Adriamycin (or Doxorubicin), Cyclophosphamide, and Etoposide.
Pronunciation
DT-PACE: /diː tiː peɪs/
Etymology
The term DT-PACE is an acronym derived from the names of the drugs used in the regimen.
Chemotherapy Regimen
Chemotherapy is a type of cancer treatment that uses drugs to kill cancer cells. DT-PACE is a specific regimen that includes several drugs, each with a different role:
- Dexamethasone is a corticosteroid that reduces inflammation and suppresses the immune system.
- Thalidomide is an immunomodulatory drug that inhibits the growth of new blood vessels, thereby starving the cancer cells.
- Cisplatin (or Platinol) is a platinum-containing drug that interferes with the DNA in cancer cells, preventing them from dividing and growing.
- Adriamycin (or Doxorubicin) is an anthracycline antibiotic that interferes with the DNA in cancer cells, preventing them from dividing and growing.
- Cyclophosphamide is an alkylating agent that damages the DNA in cancer cells, preventing them from dividing and growing.
- Etoposide is a topoisomerase inhibitor that interferes with the DNA in cancer cells, preventing them from dividing and growing.
Related Terms
- Multiple Myeloma: A type of blood cancer that DT-PACE is often used to treat.
- Chemotherapy: The type of cancer treatment that DT-PACE is a part of.
- Cancer: The general term for diseases characterized by abnormal cell growth.
External links
- Medical encyclopedia article on DT-PACE
- Wikipedia's article - DT-PACE
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