Clomiphene citrate
Clomiphene Citrate
Clomiphene Citrate (pronounced kloh-MIF-een SIT-rate) is a medication used to treat infertility in women who do not ovulate, including those suffering from Polycystic Ovary Syndrome (PCOS). It is a Selective Estrogen Receptor Modulator (SERM) that increases the production of the body's gonadotropins and stimulates the maturation and release of eggs from the ovaries.
Etymology
The term "Clomiphene" is derived from two Greek words, "klōmē" meaning "break" and "phainein" meaning "to show". "Citrate" is derived from the Latin "citrus", referring to the citric acid from which it is made.
Usage
Clomiphene Citrate is typically prescribed for women who have irregular or absent menstrual cycles due to PCOS or other disorders. It works by blocking estrogen receptors in the brain, which can increase the release of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). These hormones stimulate the ovaries to produce more eggs and increase the chances of ovulation.
Related Terms
- Ovulation Induction: The process of stimulating the ovaries to produce one or more eggs, often using medications like Clomiphene Citrate.
- Anovulation: A condition where the ovaries do not release an oocyte during a menstrual cycle, which prevents ovulation.
- Estrogen: A group of hormones that play an essential role in the growth and development of female sexual characteristics and the reproductive process.
Side Effects
Common side effects of Clomiphene Citrate include hot flashes, abdominal discomfort, and mood swings. In rare cases, it can cause Ovarian Hyperstimulation Syndrome (OHSS), a condition where the ovaries swell and leak fluid into the body.
See Also
- Infertility
- Polycystic Ovary Syndrome
- Selective Estrogen Receptor Modulator
- Gonadotropins
- Follicle Stimulating Hormone
- Luteinizing Hormone
- Ovulation Induction
- Anovulation
- Estrogen
- Ovarian Hyperstimulation Syndrome
External links
- Medical encyclopedia article on Clomiphene citrate
- Wikipedia's article - Clomiphene citrate
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