Clinoril
Clinoril
Clinoril (pronounced: kli-no-ril), also known by its generic name Sulindac (pronounced: su-lin-dak), is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation caused by conditions such as arthritis, gout, and ankylosing spondylitis.
Etymology
The term "Clinoril" is a brand name, and its etymology is not publicly disclosed. The generic name "Sulindac" is derived from its chemical structure, which is a sulfoxide form of indomethacin.
Usage
Clinoril works by reducing the levels of prostaglandins, chemicals that cells produce in response to injury and certain diseases. These chemicals cause pain, swelling, and inflammation. Clinoril blocks the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower concentrations of prostaglandins. As a consequence, inflammation, pain, and fever are reduced.
Related Terms
- Nonsteroidal anti-inflammatory drug (NSAID): A class of drugs that provides analgesic and antipyretic effects, and, in higher doses, anti-inflammatory effects.
- Arthritis: A term often used to mean any disorder that affects joints.
- Gout: A form of inflammatory arthritis characterized by recurrent attacks of a red, tender, hot, and swollen joint.
- Ankylosing spondylitis: A type of arthritis that affects the spine.
Side Effects
Like all NSAIDs, Clinoril can cause a variety of side effects, including stomach ulcers, heartburn, and a tendency to bleed more easily. More serious, but less common, side effects include heart attack and stroke.
See Also
- Indomethacin: Another NSAID that is chemically related to sulindac.
- Prostaglandins: A group of lipids made at sites of tissue damage or infection that are involved in dealing with injury and illness.
External links
- Medical encyclopedia article on Clinoril
- Wikipedia's article - Clinoril
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