Chlorquinaldol

From WikiMD's medical encyclopedia

An overview of the antiseptic and antifungal agent Chlorquinaldol


Chlorquinaldol

Structural formula of Chlorquinaldol

Chlorquinaldol is a quinoline derivative with antiseptic and antifungal properties. It is commonly used in topical formulations for the treatment of skin infections and as a preservative in various pharmaceutical products.

Chemical Properties

Chlorquinaldol is a halogenated derivative of 8-hydroxyquinoline. Its chemical structure includes a chlorine atom, which contributes to its antimicrobial activity. The compound is typically synthesized through the halogenation of 8-hydroxyquinoline.

Mechanism of Action

Chlorquinaldol exerts its effects by disrupting the cell membrane integrity of microorganisms. It is effective against a broad spectrum of bacteria and fungi, making it a versatile agent in the treatment of mixed infections. The compound's ability to chelate metal ions is also thought to play a role in its antimicrobial activity.

Uses

Chlorquinaldol is used in various formulations, including creams, ointments, and powders. It is indicated for the treatment of:

In addition to its use in dermatology, chlorquinaldol is sometimes included in oral hygiene products for its antiseptic properties.

Safety and Side Effects

While generally well-tolerated, chlorquinaldol can cause local irritation in some individuals. It is important to use the compound as directed to minimize the risk of adverse effects. Prolonged use or application to large areas of skin should be avoided to prevent systemic absorption and potential toxicity.

Related Compounds

Chlorquinaldol is related to other 8-hydroxyquinoline derivatives, such as clioquinol and iodochlorhydroxyquin, which share similar antimicrobial properties.

Related pages

Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Transform your life with W8MD's budget GLP-1 injections from $125.

W8mdlogo.png
W8MD weight loss doctors team

W8MD offers a medical weight loss program to lose weight in Philadelphia. Our physician-supervised medical weight loss provides:

NYC weight loss doctor appointments

Start your NYC weight loss journey today at our NYC medical weight loss and Philadelphia medical weight loss clinics.

Linkedin_Shiny_Icon Facebook_Shiny_Icon YouTube_icon_(2011-2013) Google plus


Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD