Cervical dislocation

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Cervical Dislocation

A laboratory mouse, often used in research involving cervical dislocation.

Cervical dislocation is a method of euthanasia commonly used in laboratory settings, particularly for small animals such as mice and rats. This technique involves the dislocation of the cervical vertebrae, leading to rapid death due to the severance of the spinal cord and major blood vessels.

Procedure

The procedure of cervical dislocation requires skill and training to ensure it is performed humanely and effectively. The animal is typically held by the base of the skull, and a quick, firm pull is applied to dislocate the cervical vertebrae. This method is considered humane when performed correctly, as it results in immediate loss of consciousness and rapid death.

Applications

Cervical dislocation is primarily used in research settings where rapid and humane euthanasia is required. It is often employed in studies involving genetically modified organisms, where precise control over the timing of death is necessary for experimental purposes. The method is also used in situations where chemical euthanasia might interfere with the experimental outcomes.

Ethical Considerations

The use of cervical dislocation as a euthanasia method is subject to ethical guidelines and regulations. Organizations such as the American Veterinary Medical Association (AVMA) provide guidelines on the appropriate use of this technique. It is crucial that personnel performing cervical dislocation are properly trained to minimize animal suffering.

Alternatives

While cervical dislocation is a widely accepted method of euthanasia, alternatives such as carbon dioxide inhalation or anesthetic overdose are also used, depending on the specific requirements of the research and the species involved. These methods may be preferred in cases where cervical dislocation is not feasible or when chemical methods do not interfere with the research outcomes.

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Contributors: Prab R. Tumpati, MD