Ceruloplasmin
Ceruloplasmin
Ceruloplasmin (pronounced: /ˌsɛrʊloʊˈplæzmɪn/) is a copper-carrying protein that plays a vital role in the human body.
Etymology
The term "Ceruloplasmin" is derived from the Latin word "caeruleus" meaning "sky-blue" and the Greek word "plasma" meaning "something formed or molded". This is due to the blue color of the protein when oxidized.
Function
Ceruloplasmin is primarily involved in the transport of copper in the bloodstream. It also plays a role in iron metabolism, functioning as a ferroxidase to aid in the conversion of ferrous iron to ferric iron for incorporation into transferrin.
Clinical Significance
Abnormally low levels of ceruloplasmin are often associated with Wilson's disease, a rare inherited disorder that causes copper to accumulate in the liver, brain, and other vital organs. On the other hand, elevated levels of ceruloplasmin can be seen in inflammatory conditions, pregnancy, and in some types of cancer.
Related Terms
External links
- Medical encyclopedia article on Ceruloplasmin
- Wikipedia's article - Ceruloplasmin
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