Carbenoxolone
Carbenoxolone
Carbenoxolone (pronounced: kar-ben-ox-oh-lone) is a synthetic derivative of glycyrrhizin, a compound found in the root of the licorice plant. It is primarily used in the treatment of peptic ulcers and inflammatory bowel disease (IBD), and has been investigated for its potential use in treating Alzheimer's disease and cancer.
Etymology
The term "Carbenoxolone" is derived from the chemical structure of the compound. "Carbeno-" refers to the presence of a carbon atom, while "-xolone" is a suffix used in organic chemistry to denote a type of chemical structure known as a lactone.
Usage
Carbenoxolone is used in the treatment of peptic ulcers, a condition characterized by sores or lesions in the lining of the stomach or the first part of the small intestine. It works by inhibiting the activity of an enzyme called 11β-Hydroxysteroid dehydrogenase, which plays a role in the production of stomach acid.
In addition to its use in treating peptic ulcers, Carbenoxolone has also been used to treat inflammatory bowel disease, a group of conditions characterized by chronic inflammation of the digestive tract.
Related Terms
- Glycyrrhizin: A compound found in licorice root from which Carbenoxolone is derived.
- Peptic ulcer: A condition characterized by sores or lesions in the lining of the stomach or the first part of the small intestine.
- Inflammatory bowel disease (IBD): A group of conditions characterized by chronic inflammation of the digestive tract.
- 11β-Hydroxysteroid dehydrogenase: An enzyme that plays a role in the production of stomach acid.
External links
- Medical encyclopedia article on Carbenoxolone
- Wikipedia's article - Carbenoxolone
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