Candidate gene

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Candidate gene

A candidate gene (pronounced: /ˈkændɪdeɪt dʒiːn/) is a gene whose chromosomal location is associated with a particular phenotype or trait. The term is used in the field of genetics to denote a gene that is suspected to cause or contribute to a disease or trait under investigation.

Etymology

The term "candidate gene" is derived from the Latin word "candidatus" which means "one who aspires to an office or honor," and the Greek word "gene" which means "birth, offspring." The term is used to denote a gene that is a strong suspect for being involved in a disease or trait.

Related Terms

  • Genome-wide association study: A study in which the entire genome is scanned to find genetic variations associated with a particular disease.
  • Phenotype: The observable physical or biochemical characteristics of an organism, as determined by both genetic makeup and environmental influences.
  • Genotype: The genetic constitution of an individual organism.
  • Polymorphism (biology): The occurrence of two or more clearly different morphs or forms, also referred to as alternative phenotypes, in the population of a species.
  • Allele: One of two or more versions of a gene that are found at the same place on a chromosome.

See Also

External links

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