Canaliculus
Canaliculus (plural: canaliculi) is a small channel or duct in the body. These microscopic structures are found in various tissues and organs, playing crucial roles in different physiological processes.
Types of Canaliculi
There are several types of canaliculi in the human body, each serving a unique function:
Bone Canaliculi
Bone canaliculi are tiny channels found within the bone matrix. They connect osteocytes (bone cells) and allow for the exchange of nutrients, waste products, and signaling molecules. These canaliculi facilitate communication between osteocytes and the blood supply, ensuring the maintenance and health of bone tissue.
Liver Canaliculi
Bile canaliculi are small ducts found in the liver. They collect bile produced by hepatocytes (liver cells) and transport it to the larger bile ducts, eventually leading to the gallbladder and small intestine. This process is essential for the digestion and absorption of fats.
Lacrimal Canaliculi
Lacrimal canaliculi are part of the tear drainage system in the eye. They collect tears from the lacrimal puncta and transport them to the lacrimal sac, from where the tears drain into the nasolacrimal duct and eventually into the nasal cavity. This system helps keep the eye moist and free from debris.
Function
The primary function of canaliculi is to facilitate the transport of fluids, nutrients, and waste products between cells and their surrounding environment. This is crucial for maintaining cellular health and function. In bones, canaliculi enable the exchange of nutrients and waste between osteocytes and the blood supply. In the liver, they transport bile necessary for digestion. In the eyes, they help drain tears to keep the eyes clean and moist.
Clinical Significance
Disorders involving canaliculi can lead to various medical conditions. For example, blockages in the bile canaliculi can result in cholestasis, a condition characterized by impaired bile flow. Similarly, blockages in the lacrimal canaliculi can cause epiphora, leading to excessive tearing.
Related Pages
- Bone
- Osteocyte
- Liver
- Bile
- Hepatocyte
- Gallbladder
- Small intestine
- Eye
- Tear drainage system
- Lacrimal puncta
- Lacrimal sac
- Nasolacrimal duct
- Nasal cavity
- Cholestasis
- Epiphora
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Contributors: Prab R. Tumpati, MD