CMF (chemotherapy)

CMF is an acronym for a combination of chemotherapy drugs that includes Cyclophosphamide, Methotrexate, and Fluorouracil. This regimen is commonly used in the treatment of various types of cancer, including breast cancer and ovarian cancer.

Pronunciation

CMF is pronounced as /ˌsiː ˌem ˈef/.

Etymology

The term CMF is an acronym derived from the initial letters of the three drugs used in this chemotherapy regimen: Cyclophosphamide, Methotrexate, and Fluorouracil.

Cyclophosphamide

Cyclophosphamide is an alkylating agent that prevents the replication of DNA by cross-linking the DNA strands and thereby preventing the growth of cancer cells.

Methotrexate

Methotrexate is an antimetabolite and antifolate drug that inhibits the metabolism of folic acid, which is necessary for the synthesis of DNA, RNA, and proteins.

Fluorouracil

Fluorouracil is a pyrimidine analog that inhibits the synthesis of DNA and RNA, thereby preventing the growth and proliferation of cancer cells.

Related Terms

Chemotherapy: The use of drugs to destroy cancer cells, usually by stopping the cancer cells' ability to grow and divide.
Cancer: A group of diseases characterized by the uncontrolled growth and spread of abnormal cells.
Breast Cancer: A type of cancer that forms in the cells of the breasts.
Ovarian Cancer: A type of cancer that begins in the ovaries.

External links

Medical encyclopedia article on CMF (chemotherapy)
Wikipedia's article - CMF (chemotherapy)

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CMF (chemotherapy)