CEACAM21
CEACAM21
CEACAM21 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 21) is a member of the CEACAM family, which is part of the immunoglobulin superfamily. This family of proteins is involved in various cellular processes, including cell adhesion, immune response, and intracellular signaling.
Structure
CEACAM21 is a glycoprotein that is encoded by the CEACAM21 gene located on chromosome 19 in humans. Like other members of the CEACAM family, CEACAM21 contains immunoglobulin-like domains that facilitate its role in cell-cell adhesion and communication.
Function
The precise biological function of CEACAM21 is not fully understood, but it is believed to play a role in cell adhesion and signaling pathways. Members of the CEACAM family are known to be involved in immune response modulation, and CEACAM21 may have similar functions.
Expression
CEACAM21 is expressed in various tissues, although its expression pattern is not as well characterized as other CEACAM family members. Research is ongoing to determine the specific tissues and conditions under which CEACAM21 is expressed.
Clinical Significance
While the clinical significance of CEACAM21 is still under investigation, other CEACAM family members have been implicated in cancer progression and metastasis. CEACAM21 may have potential as a biomarker for certain diseases or as a target for therapeutic intervention.
Research
Current research on CEACAM21 is focused on elucidating its role in cellular processes and its potential involvement in disease. Studies are being conducted to understand its interactions with other proteins and its impact on cell signaling pathways.
See Also
References
External Links
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Contributors: Prab R. Tumpati, MD