CD53
CD53 is a protein that in humans is encoded by the CD53 gene. CD53 is a member of the tetraspanin family, a group of proteins involved in various cellular processes including cell adhesion and signal transduction.
Function[edit]
CD53 is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation.
Clinical significance[edit]
Mutations in the CD53 gene have been associated with recurrent infections, suggesting a role in the immune system's response to pathogens. Further research is needed to fully understand the implications of these mutations and their potential role in immune disorders.
Interactions[edit]
CD53 has been shown to interact with:
See also[edit]
References[edit]
External links[edit]
- CD53 at GeneCards
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