C3 glomerulonephritis

C3 Glomerulonephritis

C3 Glomerulonephritis (pronounced as: C three glo-mer-u-lo-ne-fri-tis) is a rare kidney disease characterized by the deposition of C3 proteins in the glomeruli (pronounced as: glo-mer-u-li), the tiny blood vessels in the kidneys that filter waste from the blood.

Etymology

The term "C3 Glomerulonephritis" is derived from the name of the protein 'C3' that is deposited in the glomeruli, and 'glomerulonephritis', a term that refers to inflammation of the glomeruli. The term 'glomerulonephritis' itself is derived from the Greek words 'glomerulus' meaning 'small ball', and 'nephros' meaning 'kidney', with '-itis' being a common suffix in medical terminology indicating inflammation.

Definition

C3 Glomerulonephritis is a form of glomerulonephritis that is caused by problems with the body's immune system. Specifically, it is caused by the uncontrolled activation of the complement system, a part of the immune system that helps or “complements” the ability of antibodies and phagocytic cells to clear pathogens from an organism.

Symptoms

Symptoms of C3 Glomerulonephritis can vary widely, but often include hematuria (blood in the urine), proteinuria (excess protein in the urine), and decreased kidney function, which can lead to edema (swelling), high blood pressure, and in severe cases, kidney failure.

Treatment

Treatment for C3 Glomerulonephritis typically involves medications to control high blood pressure and reduce proteinuria, as well as immunosuppressive drugs to control the activity of the immune system. In severe cases, dialysis or kidney transplantation may be necessary.

Related Terms

• Glomerulus
• Glomerulonephritis
• Complement system
• Hematuria
• Proteinuria
• Edema
• Kidney failure
• Dialysis

External links

• Medical encyclopedia article on C3 glomerulonephritis
• Wikipedia's article - C3 glomerulonephritis

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