Bromethalin
Bromethalin
Bromethalin (pronounced broh-METH-uh-lin) is a potent rodenticide that is not anticoagulant. It was developed and introduced in the United States in 1985 by the EPA (Environmental Protection Agency) to combat a world-wide problem of rodent resistance to warfarin-like anticoagulant rodenticides.
Etymology
The term "Bromethalin" is derived from its chemical composition. It is a combination of the words "bromine" and "methyl", which are two of the main components in its chemical structure.
Usage
Bromethalin is used primarily as a rodenticide. It is highly toxic to rodents, causing a rapid death. It is often used in situations where rodents have developed resistance to anticoagulant rodenticides.
Mechanism of Action
Bromethalin's mode of action is to uncouple oxidative phosphorylation, which leads to a decrease in adenosine triphosphate (ATP) synthesis. The decrease in ATP inhibits the ability of nerve cells to transmit impulses, leading to paralysis, convulsions, and death.
Related Terms
- Rodenticide: A pesticide or chemical agent used to kill rodents.
- Anticoagulant: A substance that prevents or reduces coagulation of blood, prolonging the clotting time.
- Oxidative Phosphorylation: The metabolic pathway in which cells use enzymes to oxidize nutrients, thereby releasing energy.
- Adenosine Triphosphate (ATP): A complex organic chemical that provides energy to drive many processes in living cells.
See Also
External links
- Medical encyclopedia article on Bromethalin
- Wikipedia's article - Bromethalin
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