Biological marker
Biological marker
A Biological marker (pronounced: /baɪəˈlɒdʒɪkəl ˈmɑːrkər/), often referred to as a biomarker, is a measurable indicator of some biological state or condition. The term is also occasionally used to refer to a substance whose detection indicates a particular disease state, for example, the presence of an antibody may indicate an infection.
Etymology
The term "biological marker" is derived from the Greek words "bios" meaning life, and "marka" meaning a sign or indication. The term was first used in the medical field in the late 20th century.
Related Terms
- Bioindicator: An organism or biological response that reveals the presence of the pollutants by the occurrence of typical symptoms or measurable responses.
- Biomonitoring: The measurement of the body burden of toxic chemical compounds, elements, or their metabolites, in biological substances.
- Biological target: Anything within a living organism to which some other entity (like an endogenous ligand or a drug) is directed and/or binds, resulting in a change in its behavior or function.
- Clinical endpoint: A characteristic or variable that reflects how a patient feels, functions, or survives.
- Surrogate endpoint: A measure of effect of a specific treatment that may correlate with a real clinical endpoint but does not necessarily have a guaranteed relationship.
See Also
External links
- Medical encyclopedia article on Biological marker
- Wikipedia's article - Biological marker
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