Biliary pruritus
Biliary Pruritus
Biliary pruritus (pronunciation: /ˈbɪliˌɛri ˈprʊrɪtəs/), also known as cholestatic pruritus, is a condition characterized by intense itching due to a buildup of bile acids in the body.
Etymology
The term "biliary pruritus" is derived from the Latin word "bilis" meaning "bile", and the Greek word "pruritus" meaning "itching".
Definition
Biliary pruritus is a symptom of various liver diseases and biliary diseases, including primary biliary cholangitis and primary sclerosing cholangitis. It is caused by the accumulation of bile acids in the skin due to impaired bile flow, also known as cholestasis.
Symptoms
The primary symptom of biliary pruritus is intense itching, which can be generalized or localized. Other symptoms may include jaundice, dark urine, pale stools, and fatigue.
Diagnosis
Diagnosis of biliary pruritus involves a thorough medical history, physical examination, and laboratory tests to measure levels of bile acids and other liver enzymes. Imaging studies such as ultrasound, CT scan, or MRI may also be used to visualize the liver and bile ducts.
Treatment
Treatment for biliary pruritus aims to reduce the levels of bile acids in the body and alleviate itching. This may involve medications such as ursodeoxycholic acid, cholestyramine, or rifampicin. In severe cases, procedures to divert bile flow or liver transplantation may be considered.
Related Terms
- Cholestasis
- Primary biliary cholangitis
- Primary sclerosing cholangitis
- Liver disease
- Biliary disease
External links
- Medical encyclopedia article on Biliary pruritus
- Wikipedia's article - Biliary pruritus
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