Bidomain model
Bidomain Model
The Bidomain Model (pronunciation: bi-do-main model) is a mathematical model used in Biophysics and Computational Biology to simulate the electrical properties of Cardiac Tissue. It is a significant tool in understanding the complex electrical activities of the heart, particularly in the study of Cardiac Electrophysiology.
Etymology
The term "Bidomain" is derived from the Latin prefix "bi-" meaning two, and the English word "domain". This refers to the two domains that the model represents: the intracellular space (inside the cell) and the extracellular space (outside the cell).
Description
The Bidomain Model represents cardiac tissue as two continuous, overlapping domains: the intracellular and extracellular spaces. Each domain has its own distinct electrical properties, and the model accounts for the interaction between these two domains. The model is based on the Hodgkin-Huxley Model, which describes the electrical activity of a single cell, but extends this to a three-dimensional tissue level.
Related Terms
- Monodomain Model: A simpler model that assumes the intracellular and extracellular spaces have the same electrical properties.
- Hodgkin-Huxley Model: A mathematical model that describes how action potentials in neurons are initiated and propagated.
- Cardiac Electrophysiology: The study of the electrical properties of the heart.
- Computational Biology: The use of computational methods to analyze biological data.
- Biophysics: The study of biological systems using the principles of physics.
See Also
External links
- Medical encyclopedia article on Bidomain model
- Wikipedia's article - Bidomain model
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