Berefrine
Berefrine is a pharmacological agent that belongs to the class of sympathomimetic drugs. It is primarily used as a vasoconstrictor and bronchodilator. Berefrine is not widely used in modern medicine due to the development of more effective and safer alternatives.
Pharmacology
Berefrine acts on the adrenergic receptors in the body, specifically the alpha and beta receptors. It mimics the action of norepinephrine, a naturally occurring neurotransmitter in the body. By stimulating these receptors, Berefrine causes vasoconstriction, which increases blood pressure, and bronchodilation, which improves airflow to the lungs.
Medical Uses
Historically, Berefrine was used in the treatment of conditions such as asthma and hypotension. As a bronchodilator, it was used to relieve the symptoms of asthma by relaxing the muscles in the airways and increasing airflow to the lungs. As a vasoconstrictor, it was used to increase blood pressure in patients suffering from hypotension.
Side Effects
Like other sympathomimetic drugs, Berefrine can cause a range of side effects. These can include tachycardia (rapid heart rate), hypertension (high blood pressure), palpitations, and anxiety. Due to these potential side effects and the development of safer alternatives, Berefrine is not commonly used in modern medicine.
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Contributors: Prab R. Tumpati, MD