Autogenous vaccines
Autogenous Vaccines
Autogenous vaccines (pronunciation: au·to·ge·nous vac·cines, /ɔːˈtɒdʒɪnəs vaksɪːnz/) are a type of vaccine that are produced from bacteria or viruses obtained from a patient and then administered back to the same patient to stimulate an immune response. The term "autogenous" is derived from the Greek words "auto" meaning self and "genes" meaning produced.
History
The concept of autogenous vaccines dates back to the late 19th century when Robert Koch, a German physician and microbiologist, introduced the idea of using bacteria from a patient's own infection to create a personalized vaccine. This approach was later refined and expanded upon by other researchers in the field of immunology.
Production
The production of autogenous vaccines involves isolating the causative organism from the patient, growing it in a laboratory, and then inactivating it to create the vaccine. This process ensures that the vaccine is specifically tailored to the patient's infection, increasing the likelihood of a successful immune response.
Uses
Autogenous vaccines are primarily used in veterinary medicine, particularly in the treatment of bacterial infections in livestock. They are also used in human medicine, although less commonly, for conditions such as recurrent urinary tract infections and chronic sinusitis.
Advantages and Disadvantages
The main advantage of autogenous vaccines is their specificity. Because they are made from the patient's own infection, they are highly specific to the causative organism and can therefore provide a targeted immune response. However, the production of autogenous vaccines is time-consuming and costly, which can limit their use in some settings.
Related Terms
External links
- Medical encyclopedia article on Autogenous vaccines
- Wikipedia's article - Autogenous vaccines
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