Atracurium besilate
Atracurium Besilate
Atracurium Besilate (pronounced as a-tra-KYOO-ree-um BE-si-late) is a non-depolarizing neuromuscular-blocking agent used primarily in the practice of anesthesia to induce muscle relaxation during surgery or mechanical ventilation.
Etymology
The term 'Atracurium' is derived from its chemical structure, which is a bisquaternary ammonium compound. 'Besilate' refers to the besylate salt form of the drug, which is used for its stability and solubility.
Pharmacology
Atracurium Besilate works by blocking the action of acetylcholine, a neurotransmitter that transmits signals in the nervous system. By inhibiting the action of acetylcholine, Atracurium Besilate prevents nerve impulses from reaching the muscles, thereby causing muscle relaxation.
Clinical Use
Atracurium Besilate is used in a clinical setting to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. It is also used in intensive care units to manage patients requiring mechanical ventilation for longer periods.
Related Terms
- Neuromuscular-blocking agent
- Anesthesia
- Acetylcholine
- Endotracheal intubation
- Mechanical ventilation
See Also
External links
- Medical encyclopedia article on Atracurium besilate
- Wikipedia's article - Atracurium besilate
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