Arneth count
Arneth count is a method of classifying neutrophils, a type of white blood cell, based on the number of lobes in their nucleus. This count is named after the Austrian physician Joseph Arneth.
Overview
The Arneth count is used in the field of hematology to help diagnose certain medical conditions. It involves counting the number of lobes in the nucleus of a neutrophil, which can vary from two to five. The percentage of neutrophils with each number of lobes is then calculated.
Clinical significance
An increased percentage of neutrophils with more lobes (a "shift to the right") can indicate certain conditions, such as infection, inflammation, or cancer. Conversely, a higher percentage of neutrophils with fewer lobes (a "shift to the left") can suggest conditions such as vitamin B12 deficiency or folic acid deficiency.
Procedure
To perform an Arneth count, a blood sample is taken and a blood smear is prepared. The smear is then stained and examined under a microscope. The number of lobes in the nucleus of each neutrophil is counted and the percentages are calculated.
Limitations
While the Arneth count can provide useful information, it is not a definitive diagnostic tool. Other tests and clinical information are often needed to make a diagnosis. In addition, the count can be influenced by factors such as the age of the blood sample and the staining technique used.
See also
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Contributors: Prab R. Tumpati, MD