Apiol
Apiol is a phenylpropanoid and a terpenoid, and is considered a minor cannabis constituent. It is found in parsley and in the oil of the dill plant. Apiol was first isolated from the fruit of the parsley plant in the early 20th century. It has been used historically as an abortifacient and a menstrual flow stimulant in folk medicine.
History
Apiol was first isolated in 1855 by Joret and Homolle, two French chemists. They named it after the plant from which it was extracted, the parsley plant (Petroselinum crispum), whose Latin name is Apium. In the early 20th century, it was used in the form of a crude extract from parsley seeds to induce abortion.
Chemical Properties
Apiol is a phenylpropanoid and a terpenoid. It is a yellowish, oily liquid that is soluble in water and alcohol. Its chemical formula is C12H14O4. It has a characteristic strong smell and a spicy taste.
Biological Effects
Apiol has been used historically as an abortifacient and a menstrual flow stimulant in folk medicine. It is also known to have antibacterial properties. However, its use as a medicine is not recommended due to its potential toxicity.
Toxicity
Apiol is potentially toxic and can cause liver and kidney damage if ingested in large amounts. It can also cause allergic reactions in some individuals.
See Also
References
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Contributors: Prab R. Tumpati, MD