Apararenone
Apararenone
Apararenone (pronounced: a-par-a-ren-one) is a non-steroidal, selective mineralocorticoid receptor antagonist (MRA) used in the treatment of various cardiovascular diseases.
Etymology
The term "Apararenone" is derived from the Latin roots "apara", meaning "to ward off", and "renone", referring to the renal system. This reflects the drug's function in inhibiting the action of mineralocorticoid hormones on the kidney.
Usage
Apararenone is primarily used in the treatment of heart failure, hypertension, and liver cirrhosis with ascites. It works by blocking the action of aldosterone, a hormone that increases the reabsorption of sodium and water and the release of potassium in the kidneys. This helps to reduce fluid build-up in the body, lower blood pressure, and decrease the risk of cardiovascular events.
Related Terms
- Mineralocorticoid receptor antagonist (MRA): A class of drugs that block the action of mineralocorticoid hormones in the body. Apararenone is a selective MRA, meaning it specifically targets the mineralocorticoid receptors in the kidneys.
- Aldosterone: A hormone produced by the adrenal glands that increases the reabsorption of sodium and water and the release of potassium in the kidneys. Apararenone works by blocking the action of this hormone.
- Heart failure: A condition in which the heart is unable to pump enough blood to meet the body's needs. Apararenone is used to treat heart failure by reducing fluid build-up in the body.
- Hypertension: Also known as high blood pressure, this is a condition in which the force of the blood against the artery walls is too high. Apararenone is used to treat hypertension by lowering blood pressure.
- Liver cirrhosis: A late stage of scarring (fibrosis) of the liver caused by many forms of liver diseases and conditions. Apararenone is used to treat liver cirrhosis with ascites by reducing fluid build-up in the body.
- Ascites: An abnormal build-up of fluid in the abdomen. Apararenone is used to treat ascites associated with liver cirrhosis.
External links
- Medical encyclopedia article on Apararenone
- Wikipedia's article - Apararenone
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