Antinociceptive
Antinociceptive
Antinociceptive (pronounced: an-ti-no-si-sep-tiv) is a term used in the field of medicine and pharmacology to describe the action or effect of a substance in reducing sensitivity to painful stimuli or inhibiting the perception of pain.
Etymology
The term "antinociceptive" is derived from the prefix 'anti-', meaning against, and 'nociceptive', which refers to the sensory nervous system's response to harmful or potentially harmful stimuli.
Related Terms
- Nociception: The sensory nervous system's response to certain harmful or potentially harmful stimuli.
- Analgesic: A type of medication that is used to relieve pain.
- Pain threshold: The minimum point at which a person begins to feel pain.
- Pain tolerance: The maximum amount of pain that a person can withstand.
Antinociceptive Agents
Antinociceptive agents are substances that reduce sensitivity to painful stimuli. They can be endogenous (produced within the body) or exogenous (originating from outside the body). Examples of antinociceptive agents include:
- Opioids: These are a class of drugs that include the illegal drug heroin, synthetic opioids such as fentanyl, and pain relievers available legally by prescription, such as oxycodone (OxyContin®), hydrocodone (Vicodin®), codeine, morphine, and many others.
- Nonsteroidal anti-inflammatory drugs (NSAIDs): These are drugs with analgesic, antipyretic, and, in higher doses, anti-inflammatory effects.
- Endorphins: These are endogenous opioid neuropeptides and peptide hormones in humans and other animals. They are produced by the central nervous system and the pituitary gland.
See Also
External links
- Medical encyclopedia article on Antinociceptive
- Wikipedia's article - Antinociceptive
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