Antagonists
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Antagonists
Antagonists (/ænˈtæɡənɪsts/) are a type of drug or other substance that inhibits the physiological actions of another, particularly a receptor antagonist.
Etymology
The term "antagonist" comes from the Greek word "antagonistes", which means "opponent" or "rival". In the context of pharmacology, it refers to a substance that counteracts the effects of another substance.
Types of Antagonists
There are several types of antagonists, including:
- Competitive antagonist: This type of antagonist binds to the same site as the agonist, but does not activate it. Instead, it blocks the agonist's access to the site.
- Non-competitive antagonist: This type of antagonist binds to a different site than the agonist. It changes the shape of the receptor and makes it less responsive to the agonist.
- Uncompetitive antagonist: This type of antagonist binds to the receptor only after the agonist has bound. It locks the receptor in a state that is less responsive to the agonist.
- Inverse agonist: This type of antagonist binds to the same receptor as the agonist and induces a pharmacological response opposite to that of the agonist.
Related Terms
- Agonist: A substance that initiates a physiological response when combined with a receptor.
- Receptor: A protein molecule that receives chemical signals from outside a cell.
- Pharmacology: The branch of medicine concerned with the uses, effects, and modes of action of drugs.
- Drug: A substance used in the diagnosis, treatment, or prevention of a disease or as a component of a medication.
External links
- Medical encyclopedia article on Antagonists
- Wikipedia's article - Antagonists
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