Amnion nodosum

Amnion Nodosum

Amnion Nodosum (/æmniːɒn noʊdoʊsʊm/), is a rare pathological condition characterized by the presence of multiple, small, white or yellow nodules on the amniotic membrane.

Etymology

The term "Amnion Nodosum" is derived from two Latin words: "Amnion", which refers to the innermost layer of the placenta, and "Nodosum", which means "knotted" or "nodular".

Pathogenesis

Amnion Nodosum is typically associated with fetal conditions that lead to decreased swallowing or increased production of amniotic fluid, such as renal agenesis and tracheoesophageal fistula. The nodules are thought to be formed by the accumulation of squamous cells shed from the fetal skin into the amniotic fluid.

Clinical Significance

The presence of Amnion Nodosum is often indicative of severe underlying fetal anomalies. It is usually detected during routine ultrasound examinations during pregnancy. However, it is not a definitive diagnostic tool and further investigations are required to confirm the diagnosis.

Related Terms

• Amniotic Fluid
• Amniotic Membrane
• Renal Agenesis
• Tracheoesophageal Fistula
• Ultrasound

External links

• Medical encyclopedia article on Amnion nodosum
• Wikipedia's article - Amnion nodosum

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