Ammonium lactate
A chemical compound used in dermatology
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Overview
Ammonium lactate is a chemical compound that is commonly used in dermatology. It is the ammonium salt of lactic acid, and it is often used in topical formulations to treat xerosis (dry skin) and ichthyosis.
Chemical Properties
Ammonium lactate is composed of ammonium ions and lactate ions. The chemical formula is C3H9NO3. It is a colorless to pale yellow liquid with a mild odor. The compound is hygroscopic, meaning it can absorb moisture from the air.
Mechanism of Action
Ammonium lactate works by increasing the moisture content of the skin. It acts as a keratolytic agent, which means it helps to break down and remove the outer layer of dead skin cells. This action helps to soften and smooth the skin, making it effective in treating conditions like xerosis and ichthyosis.
Uses in Dermatology
Ammonium lactate is used in various topical formulations, such as creams and lotions. It is often prescribed for:
- Xerosis: To alleviate dry, scaly skin.
- Ichthyosis: To reduce scaling and improve skin texture.
- Keratosis pilaris: To smooth rough patches of skin.
Side Effects
Common side effects of ammonium lactate include mild skin irritation, redness, and a stinging sensation. These effects are usually temporary. Patients are advised to avoid applying the compound to broken or irritated skin.
Precautions
Patients using ammonium lactate should avoid exposure to sunlight or artificial UV rays, as the compound can increase the skin's sensitivity to light. It is also important to follow the prescribed dosage and application instructions to minimize the risk of adverse effects.
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Contributors: Prab R. Tumpati, MD