Amino acid sequence
Amino Acid Sequence
The Amino Acid Sequence (pronunciation: /ˈæmɪnoʊ ˈæsɪd ˈsiːkwəns/) is a term used in Biochemistry and Molecular Biology to describe the order of amino acids in a protein or peptide.
Etymology
The term "Amino Acid Sequence" is derived from the words "amino acid", which are organic compounds composed of nitrogen, carbon, hydrogen, and oxygen, and "sequence", which refers to the order in which these compounds are arranged.
Definition
An Amino Acid Sequence is the order in which amino acids are linked together in a protein or peptide. This sequence is determined by the genetic code in the DNA of the organism. Each amino acid is represented by a three-letter abbreviation, and the sequence is often written as a string of these abbreviations.
Related Terms
- Primary Structure: The amino acid sequence of a protein or peptide is also known as its primary structure.
- Polypeptide: A polypeptide is a single linear chain of amino acids, which can be a component of a protein.
- Proteomics: The study of the entire set of proteins expressed by a genome, including the analysis of amino acid sequences.
Importance
The Amino Acid Sequence of a protein or peptide is crucial for its function. Changes in the sequence can lead to changes in the structure and function of the protein, which can have significant effects on the organism. This is the basis for many genetic diseases, such as sickle cell anemia, where a single change in the amino acid sequence of the hemoglobin protein causes the disease.
External links
- Medical encyclopedia article on Amino acid sequence
- Wikipedia's article - Amino acid sequence
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