Amfebutamone
Amfebutamone
Amfebutamone (pronounced am-fe-bu-ta-mone), also known as Bupropion, is a medication primarily used as an antidepressant and smoking cessation aid.
Etymology
The term "Amfebutamone" is derived from its chemical name, α-methylphenethylaminobutyrophenone. It was first approved for medical use in the United States in 1985.
Usage
Amfebutamone is used to treat major depressive disorder and to support smoking cessation. It is also used off-label as a first-line treatment for ADHD and as a part of weight loss programs.
Mechanism of Action
Amfebutamone acts as a norepinephrine-dopamine reuptake inhibitor (NDRI). It does not cause sexual side effects or weight gain as other antidepressants do. However, it is associated with a risk of seizures, which made it temporarily withdrawn from the market.
Side Effects
Common side effects of Amfebutamone include dry mouth, trouble sleeping, agitation, and headaches. Serious side effects can include seizures, hallucinations, fever, fast heart rate, and abnormal liver function tests.
Related Terms
- Antidepressant
- Bupropion
- Major depressive disorder
- Smoking cessation
- ADHD
- Weight loss
- Norepinephrine-dopamine reuptake inhibitor
- Seizure
External links
- Medical encyclopedia article on Amfebutamone
- Wikipedia's article - Amfebutamone
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