African histoplasmosis
African Histoplasmosis
African histoplasmosis (pronounced: his-toh-plaz-moh-sis) is a rare infectious disease caused by the fungus Histoplasma capsulatum var. duboisii. This disease is endemic to certain regions of Africa and is characterized by the formation of granulomas in various organs, particularly the skin and bones.
Etymology
The term "histoplasmosis" is derived from the Greek words "histo" meaning tissue, "plasma" meaning form or mold, and "osis" indicating a condition or disease. The variant duboisii is named after the scientist who first identified it.
Symptoms
The symptoms of African histoplasmosis can vary greatly depending on the organs affected. Common symptoms include fever, weight loss, and skin lesions. In severe cases, the disease can affect the central nervous system leading to neurological disorders.
Diagnosis
Diagnosis of African histoplasmosis is typically made through a combination of clinical findings, laboratory tests, and imaging studies. The fungus can be identified in tissue samples using special stains and cultures.
Treatment
Treatment for African histoplasmosis typically involves long-term antifungal therapy with drugs such as amphotericin B or itraconazole. In severe cases, surgical intervention may be necessary.
Prevention
Prevention strategies for African histoplasmosis are largely focused on reducing exposure to the fungus, particularly in endemic areas. This can include wearing protective clothing and masks when in contact with soil or bird droppings, which are common sources of the fungus.
See Also
External links
- Medical encyclopedia article on African histoplasmosis
- Wikipedia's article - African histoplasmosis
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