AVN-211

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AVN-211

AVN-211 (pronounced A-V-N-two-eleven) is a novel small molecule and potent 5-HT6 receptor antagonist with potential antipsychotic activity. AVN-211 is being developed by Avineuro Pharmaceuticals for the treatment of schizophrenia and other related disorders.

Etymology

The term AVN-211 is derived from the name of the company that developed it, Avineuro Pharmaceuticals. The number 211 does not have a known specific significance and is likely a part of a series of compounds developed by the company.

Pharmacology

AVN-211 selectively binds to and blocks the activity of the 5-HT6 receptor, which may result in an improvement in cognition and negative and positive symptoms associated with schizophrenia. The 5-HT6 receptor is a subtype of the 5-HT receptor that binds the endogenous neurotransmitter serotonin, and is thought to be involved in the regulation of various cognitive processes.

Clinical Trials

AVN-211 has undergone Phase 2 clinical trials for the treatment of schizophrenia. The trials have shown promising results, with patients demonstrating significant improvements in cognitive function and a reduction in the severity of both positive and negative symptoms.

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