AP-1 transcription factor

AP-1 Transcription Factor

AP-1 Transcription Factor (pronounced as A-P-one transcription factor) is a type of protein that regulates gene expression in response to a variety of stimuli, including cytokines, growth factors, stress, and bacterial and viral infections.

Etymology

The term AP-1 stands for Activator Protein-1. This name is derived from its function as a protein that activates the transcription of genes.

Function

The AP-1 transcription factor is a dimeric complex that is composed of proteins belonging to the c-Fos, c-Jun, ATF and JDP families. These proteins bind to a specific sequence of DNA, known as the AP-1 binding site, and regulate gene expression.

Related Terms

• Transcription
• Gene expression
• Protein
• Cytokine
• Growth factor
• Stress
• Bacterial
• Viral infection
• Dimer
• c-Fos
• c-Jun
• ATF
• JDP
• DNA

External links

• Medical encyclopedia article on AP-1 transcription factor
• Wikipedia's article - AP-1 transcription factor

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