Hay–Wells syndrome
(Redirected from AEC syndrome)
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Hay–Wells syndrome | |
|---|---|
| 200px | |
| Synonyms | AEC syndrome, ankyloblepharon-ectodermal dysplasia-clefting syndrome |
| Pronounce | |
| Specialty | Medical genetics |
| Symptoms | Ankyloblepharon, ectodermal dysplasia, cleft palate, cleft lip |
| Complications | N/A |
| Onset | |
| Duration | |
| Types | |
| Causes | Genetic mutation in the TP63 gene |
| Risks | |
| Diagnosis | Clinical diagnosis, genetic testing |
| Differential diagnosis | |
| Prevention | |
| Treatment | Symptomatic treatment, surgical correction |
| Medication | |
| Prognosis | |
| Frequency | Rare |
| Deaths | |
Hay–Wells syndrome (also known as AEC syndrome) is a rare genetic disorder characterized by anodontia or hypodontia, ectodermal dysplasia, and cleft lip/palate. The syndrome is caused by mutations in the TP63 gene.
Symptoms
The symptoms of Hay–Wells syndrome can vary greatly from person to person. However, common symptoms include:
- Anodontia or hypodontia: This refers to the absence or underdevelopment of teeth.
- Ectodermal dysplasia: This is a group of conditions in which the normal development of the ectodermal tissues (including the skin, hair, nails, and sweat glands) is disturbed.
- Cleft lip/palate: This is a split in the upper lip and/or roof of the mouth that is present from birth.
Causes
Hay–Wells syndrome is caused by mutations in the TP63 gene. This gene provides instructions for making a protein that is crucial for the development and maintenance of various tissues, including the skin, hair, teeth, and sweat glands.
Diagnosis
The diagnosis of Hay–Wells syndrome is typically based on the presence of characteristic signs and symptoms. Genetic testing can confirm the diagnosis.
Treatment
There is currently no cure for Hay–Wells syndrome. Treatment is symptomatic and supportive, and may include dental implants for missing teeth, surgery for cleft lip/palate, and various interventions to manage the symptoms of ectodermal dysplasia.
See also
Transform your life with W8MD's budget GLP-1 injections from $125.
W8MD offers a medical weight loss program to lose weight in Philadelphia. Our physician-supervised medical weight loss provides:
- Most insurances accepted or discounted self-pay rates. We will obtain insurance prior authorizations if needed.
- Generic GLP1 weight loss injections from $125 for the starting dose.
- Also offer prescription weight loss medications including Phentermine, Qsymia, Diethylpropion, Contrave etc.
NYC weight loss doctor appointments
Start your NYC weight loss journey today at our NYC medical weight loss and Philadelphia medical weight loss clinics.
- Call 718-946-5500 to lose weight in NYC or for medical weight loss in Philadelphia 215-676-2334.
- Tags:NYC medical weight loss, Philadelphia lose weight Zepbound NYC, Budget GLP1 weight loss injections, Wegovy Philadelphia, Wegovy NYC, Philadelphia medical weight loss, Brookly weight loss and Wegovy NYC
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
