ADB-HEXINACA
ADB-HEXINACA is a synthetic cannabinoid that belongs to the indazole-3-carboxamide family. It is a potent agonist of the cannabinoid receptors, specifically the CB1 and CB2 receptors. ADB-HEXINACA is often used in scientific research to study the effects of cannabinoids on the human body and the endocannabinoid system.
Chemical Structure
ADB-HEXINACA has a chemical structure that includes an indazole core, which is a common feature among synthetic cannabinoids. The full chemical name of ADB-HEXINACA is N-1-amino-3,3-dimethyl-1-oxobutan-2-yl-1-(cyclohexylmethyl)-1H-indazole-3-carboxamide. The presence of the cyclohexylmethyl group distinguishes it from other synthetic cannabinoids.
Pharmacology
As a potent agonist of the CB1 and CB2 receptors, ADB-HEXINACA mimics the effects of tetrahydrocannabinol (THC), the primary psychoactive component of cannabis. It binds to these receptors with high affinity, leading to various physiological and psychoactive effects. The exact pharmacokinetics and metabolism of ADB-HEXINACA are still under investigation.
Legal Status
The legal status of ADB-HEXINACA varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of medical use. Researchers must obtain special licenses to study this compound legally.
Health Effects and Risks
The health effects and risks associated with ADB-HEXINACA are not fully understood. However, synthetic cannabinoids, in general, have been linked to severe adverse effects, including psychosis, tachycardia, and seizures. Long-term use may lead to dependence and other health complications.
Research Applications
ADB-HEXINACA is primarily used in scientific research to explore the endocannabinoid system and the potential therapeutic applications of cannabinoids. It helps in understanding the interaction between synthetic cannabinoids and cannabinoid receptors, which can lead to the development of new medications.
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Contributors: Prab R. Tumpati, MD