ADB-BINACA

ADB-BINACA

Chemical structure of ADB-BINACA

ADB-BINACA is a synthetic cannabinoid that has been used as a designer drug. It is a potent agonist of the cannabinoid receptors, which are part of the endocannabinoid system in the human body. ADB-BINACA is often found in "spice" or "K2" products, which are marketed as legal alternatives to cannabis.

Chemical Structure

ADB-BINACA is classified as an indazole-based synthetic cannabinoid. Its chemical structure includes an indazole core, which is a bicyclic structure composed of a benzene ring fused to a pyrazole ring. The compound also contains an amide linkage and a tert-butyl group, which contribute to its high affinity for cannabinoid receptors.

Pharmacology

ADB-BINACA acts as a full agonist at the CB1 and CB2 cannabinoid receptors. These receptors are part of the G protein-coupled receptor family and are primarily involved in the modulation of neurotransmitter release in the central nervous system. The activation of these receptors by ADB-BINACA can lead to psychoactive effects similar to those of tetrahydrocannabinol (THC), the primary active component of cannabis.

Legal Status

Due to its potential for abuse and lack of medical use, ADB-BINACA has been classified as a controlled substance in many countries. The legal status of synthetic cannabinoids like ADB-BINACA varies widely, with some jurisdictions implementing blanket bans on entire classes of compounds to prevent the proliferation of new designer drugs.

Health Effects

The use of ADB-BINACA has been associated with a range of adverse health effects. These can include tachycardia, hypertension, nausea, vomiting, anxiety, and hallucinations. In severe cases, the use of synthetic cannabinoids can lead to seizures, renal failure, and even death.

Related Pages

• Synthetic cannabinoids
• Cannabinoid receptor
• Endocannabinoid system
• Spice (drug)
• K2 (drug)