ABCB6

ABCB6 is a gene that encodes a protein in the ATP-binding cassette transporter family. This family is one of the largest and most diverse families of proteins. The ABCB6 protein is involved in several important biological processes, including cellular transport, lipid metabolism, and drug resistance.

Function

The ABCB6 protein is a member of the ATP-binding cassette transporter family. These proteins transport various molecules across extra- and intra-cellular membranes. The ABCB6 protein is thought to play a role in mitochondrial function and heme biosynthesis. Heme is a vital component of hemoglobin, the molecule that carries oxygen in the blood.

Clinical significance

Mutations in the ABCB6 gene have been associated with a number of medical conditions. These include colorectal cancer, lung cancer, and ocular melanoma. In addition, ABCB6 has been implicated in drug resistance, particularly in the context of chemotherapy.

Research

Research into the ABCB6 gene and its associated protein is ongoing. Current areas of focus include the role of ABCB6 in cancer development and progression, as well as its potential as a target for cancer therapy.

See also

• ATP-binding cassette transporter
• Gene
• Protein
• Heme biosynthesis
• Mitochondrial function

References

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