5' end
5' end
The 5' end (pronounced "five prime end") refers to the end of a DNA or RNA strand that has the fifth carbon in the sugar-ring of the deoxyribose or ribose at its terminus.
Pronunciation
- Five prime end
Etymology
The term "5' end" originates from the nomenclature used in molecular biology to describe the structure of nucleic acids. The 5' and 3' designations refer to the numbering of carbons in the ribose sugar ring, which forms the backbone of the nucleic acid molecule.
Related Terms
- 3' end: The opposite end of the nucleic acid strand to the 5' end. It is the end of the DNA or RNA strand that has the third carbon in the sugar-ring of the deoxyribose or ribose at its terminus.
- Phosphate group: A functional group that is attached to the 5' end of a nucleic acid molecule.
- Hydroxyl group: A functional group that is attached to the 3' end of a nucleic acid molecule.
- Nucleotide: The basic building block of nucleic acids, consisting of a five-carbon sugar, a phosphate group, and a nitrogenous base.
- DNA: Deoxyribonucleic acid, the molecule that carries genetic information in all living organisms (except some viruses).
- RNA: Ribonucleic acid, a molecule similar to DNA but with a slightly different chemical structure. It plays several key roles in the process of translating genetic information from DNA into protein products.
External links
- Medical encyclopedia article on 5' end
- Wikipedia's article - 5' end
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