3,4-Methylenedioxy-N-methylphentermine

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Chemical compound related to MDMA


3,4-Methylenedioxy-N-methylphentermine (MDMP) is a chemical compound that belongs to the class of substituted amphetamines. It is structurally related to MDMA (3,4-methylenedioxy-N-methylamphetamine), a well-known psychoactive drug. MDMP is of interest in the field of psychopharmacology due to its potential effects on the central nervous system, although it is not as widely studied or used as MDMA.

Chemical Structure and Properties

Chemical structure of 3,4-Methylenedioxy-N-methylphentermine

MDMP is characterized by the presence of a methylenedioxy group attached to the phenyl ring, similar to MDMA. The chemical formula for MDMP is C11H15NO2, and it has a molecular weight of 193.24 g/mol. The compound is a derivative of phentermine, with the addition of a methylenedioxy group, which is believed to influence its pharmacological properties.

Pharmacology

MDMP is thought to act as a central nervous system stimulant, similar to other substituted amphetamines. The presence of the methylenedioxy group suggests that it may have effects on the serotonin system, potentially acting as a serotonin releasing agent. However, detailed studies on its pharmacodynamics and pharmacokinetics are limited.

Mechanism of Action

The exact mechanism of action of MDMP is not well understood, but it is hypothesized to involve the release of monoamines such as serotonin, dopamine, and norepinephrine. This is similar to the action of MDMA, which is known to increase the release of these neurotransmitters, leading to its psychoactive effects.

Potential Effects

While specific studies on MDMP are scarce, it is likely that its effects would be similar to those of other methylenedioxy-substituted amphetamines. These effects may include increased energy, euphoria, and altered sensory perception. However, without empirical data, these effects remain speculative.

Legal Status

The legal status of MDMP varies by country. In many jurisdictions, it may be classified under analog laws that regulate substances similar to controlled drugs like MDMA. It is important for researchers and users to be aware of the legal implications of possessing or using MDMP.

Research and Development

Research on MDMP is limited, and it is not a widely studied compound. Interest in MDMP may arise from its structural similarity to MDMA, which has been the subject of extensive research for its potential therapeutic applications, particularly in the treatment of post-traumatic stress disorder (PTSD).

Related Compounds

MDMP is part of a broader class of methylenedioxy-substituted amphetamines, which includes:

  • MDMA
  • MDA (3,4-methylenedioxyamphetamine)
  • MDEA (3,4-methylenedioxy-N-ethylamphetamine)

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Contributors: Prab R. Tumpati, MD