2C-H

2C-H

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Chemical structure of 2C-H

2C-H (2,5-dimethoxyphenethylamine) is a psychedelic phenethylamine of the 2C family. It is the base compound for a series of psychedelic phenethylamines, which include 2C-B, 2C-I, and 2C-E.

2C-H is a synthetic compound that was first synthesized by Alexander Shulgin. It is known for its role as a precursor in the synthesis of other 2C compounds, but it is not commonly used as a recreational drug due to its relatively mild effects compared to its derivatives.

Chemical Properties

2C-H is a phenethylamine with two methoxy groups attached to the benzene ring at the 2 and 5 positions. Its chemical formula is C10H15NO2. The presence of the methoxy groups is a defining feature of the 2C family of compounds.

Pharmacology

2C-H acts primarily as a serotonin receptor agonist, similar to other compounds in the 2C series. However, its affinity for these receptors is lower than that of its more potent derivatives, such as 2C-B and 2C-I. This results in a less intense psychedelic experience.

Synthesis

2C-H can be synthesized from 2,5-dimethoxybenzaldehyde through a series of chemical reactions. The synthesis typically involves the formation of a nitrostyrene intermediate, which is then reduced to the final phenethylamine product.

Legal Status

The legal status of 2C-H varies by country. In some jurisdictions, it is classified as a controlled substance due to its structural similarity to other psychoactive compounds. In others, it may be legal or unregulated.

Related Compounds

2C-H is the parent compound of the 2C series, which includes a variety of other phenethylamines with different substituents on the benzene ring. Some notable derivatives include:

• 2C-B
• 2C-I
• 2C-E

These compounds are known for their psychedelic effects and have been used in both recreational and research settings.

Related Pages

• Phenethylamine
• Psychedelic drug
• Alexander Shulgin