Α-Viniferin
Α-Viniferin is a stilbenoid, a type of natural phenol, and a phytoalexin. It can be found in Vitis vinifera (grapevine) and is produced in response to infection or injury.
Chemical Structure
Α-Viniferin is a trimer of resveratrol, a type of stilbenoid. It is formed by the condensation of three molecules of resveratrol, resulting in a cyclic structure. The chemical formula of α-viniferin is C42H30O9.
Biosynthesis
Α-Viniferin is synthesized in plants from resveratrol through the action of the enzyme stilbene synthase. This enzyme catalyzes the condensation of three molecules of resveratrol to form α-viniferin.
Biological Activity
Α-Viniferin has been found to have several biological activities. It has antioxidant properties, and can scavenge free radicals, potentially protecting cells from oxidative damage. It also has anti-inflammatory effects, and can inhibit the production of pro-inflammatory cytokines. In addition, α-viniferin has been found to have antifungal activity, and can inhibit the growth of several types of fungi.
Potential Therapeutic Uses
Due to its biological activities, α-viniferin has potential therapeutic uses. Its antioxidant and anti-inflammatory properties suggest that it could be used in the treatment of diseases associated with oxidative stress and inflammation, such as cardiovascular disease and cancer. Its antifungal activity also suggests that it could be used in the treatment of fungal infections.
See Also
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Contributors: Prab R. Tumpati, MD